2-(Trifluoroacetyl)pyridine (contains gem-diol)

2-(Trifluoroacetyl)pyridine (contains gem-diol) - Names and Identifiers

Name	2-(Trifluoroacetyl)pyridine
Synonyms	2-trifluoroacetypyridine 2-(Trifluoroacetyl)pyridine 2,2,2-trifluoro-1-(2-pyridinyl)Ethanone 2,2,2-trifluoro-1-(pyridin-2-yl)ethanone Ethanone, 2,2,2-trifluoro-1-(2-pyridinyl)- 2,2,2-trifluoro-1-(pyridin-2-yl)ethan-1-one 2-(Trifluoroacetyl)pyridine (contains gem-diol) Ethanone, 2,2,2-trifluoro-1-(2-pyridinyl)- (9CI)
CAS	33284-17-2
InChI	InChI=1/C7H4F3NO/c8-7(9,10)6(12)5-3-1-2-4-11-5/h1-4H

2-(Trifluoroacetyl)pyridine (contains gem-diol) - Physico-chemical Properties

Molecular Formula	C7H4F3NO
Molar Mass	175.11
Density	1.341±0.06 g/cm3(Predicted)
Boling Point	172.9±35.0 °C(Predicted)
Flash Point	58.4°C
Vapor Presure	1.3mmHg at 25°C
pKa	0.95±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.446

2-(Trifluoroacetyl)pyridine (contains gem-diol) - Introduction

2-(Trifluoroacetyl)pyridine is an organic compound with the chemical formula C7H4F3NO and a molecular weight of 173.11. Its nature is as follows:

1. Appearance: 2-(Trifluoroacetyl)pyridine is a colorless to yellow liquid.
2. Melting Point: About -25 ° C.
3. Boiling Point: about 159-160 ° C.
4. Density: About 1.34g/cm3.
5. Solubility: 2-(Trifluoroacetyl)pyridine is soluble in common organic solvents, such as alcohols, ethers and ketones.

2-(Trifluoroacetyl)pyridine has the following uses in laboratory and industrial production:

1. As a chemical reagent: 2-(Trifluoroacetyl)pyridine can be used as an important reagent for the synthesis of organic compounds, commonly used in the introduction of pyridine rings and as a reagent carrier in organic synthesis.

The preparation method of 2-(Trifluoroacetyl)pyridine can be carried out by the following steps:

1. Reaction of pyridine and trifluoroacetic anhydride: Dissolve pyridine in chlorinated methane, then add trifluoroacetic anhydride, and react at room temperature.
2. After completion of the reaction, 2-(Trifluoroacetyl)pyridine was purified by distillation.

Regarding the safety information of 2-(Trifluoroacetyl)pyridine, the following are some regular precautions:

1.2-(Trifluoroacetyl)pyridine may be irritating to the eyes, skin and respiratory system, so it is necessary to wear appropriate protective measures when using it, such as wearing gloves, breathing mask and goggles.
2. Avoid direct contact with 2-(Trifluoroacetyl)pyridine, and try to avoid inhaling its vapor or dust.
3. When using and storing 2-(Trifluoroacetyl)pyridine, keep it well ventilated and avoid operation in a confined space.
4. If accidental contact or misuse, should immediately rinse with plenty of water, and seek medical help.

Last Update：2024-04-10 22:29:15